Tag: mutations

  • A Mutational Limit for Lifespan?

    It has long been known that mammalian lifespan roughly correlates with animal size, i.e. larger animals live longer than smaller ones. Mice generally live less than 2 years, your average dog lives 10-13 years, and humans have a typical lifespan of 73 years. What is less clear is the mechanistic basis for this observation. Differences […]

  • Move Over COVID, Influenza Is Coming to Town

    Seasonal influenza sweeps around the world year after year infecting millions of people across the Northern and Southern hemispheres. In a typical year, influenza causes 30-40 million cases in the United States with an average of 37,000 deaths per year from 2010-2019. However, because of the COVID-19 precautions (masks, social distancing, lockdowns, and cancellation of […]

  • COVID-19 Update – Variations on a Theme

    The news is filled with alarming stories about new variants of SARS-CoV-2 that were isolated in recent weeks. These variants are versions of the original SARS-CoV-2 virus that have acquired mutations. Mutations are a natural and regular occurrence that happens when the parental viral genome replicates during the process of making progeny viruses. In an […]

  • Human Gene Editing – Is the Future Now?

    Many human diseases are the result of genetic errors, commonly called mutations. You can think of the four nucleotides (A, C, T, and G) that comprise our DNA as the letters of our genetic alphabet with these nucleotide letters making up our genes which are the “words” of our genome. Mutations result from changes in […]